NOXAFIL 300 mg (posaconazole), triazole antifungal

INFECTIOUS DISEASE - New medicinal product
Opinions on drugs - Posted on Aug 23 2016

Reason for request

Inclusion

New presentation in concentrate for solution for infusion in addition to oral forms

  • NOXAFIL IV has Marketing Authorisation in the treatment of:

-   healing of invasive aspergillosis, fusariosis, chromoblastomycosis/mycetomas and coccidioidomycosis, in patients refractory or intolerant to first-line antifungals.

-   prophylaxis for invasive fungal infections in high-risk patients.

  • No clinical benefit demonstrated when compared with oral forms of posaconazole.
  • Its place in the therapeutic strategy is the same as that of the oral presentations currently available. The injectable form may have a benefit in patients who cannot receive oral forms.

Clinical Benefit

Substantial

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Clinical Added Value

no clinical added value

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Therapeutic use

-

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