LOJUXTA

Opinions on drugs - Posted on May 30 2014

Reason for request

Inclusion

Clinical Benefit

Substantial

The actual benefit provided by LOJUXTA in combination with other lipid lowering medicines is substantial in adult patients with homozygous familial hypercholesterolaemia (HoFH) uncontrolled by these lipid-lowering treatments used at maximum doses, whether or not combined with apheresis.

Clinical Added Value

minor

The addition of LOJUXTA to an optimal lipid-lowering therapy, used at maximum doses, whether or not combined with apheres is, in adult patients with uncontrolled homozygous familial hypercholesterolaemia (HoFH), provides a minor improvement in actual benefit (IABIV).