PENTHROX, methoxyflurane, anaesthetic for emergency analgesia

Reason for request

Clinical Benefit

Moderate

No clinical benefit demonstrated relative to other available analgesics    PENTHROX has Marketing Authorisation in the emergency relief of moderate to severe pain associated with trauma in conscious adult patients. Its analgesic superiority compared with placebo has been demonstrated in a study in patients with predominantly moderate pain. Its efficacy in case of very severe pain (NS > 7 or VAS > 70) has not been evaluated. No comparison of satisfactory methodological quality with other analgesics is available.

Clinical Added Value

no clinical added value

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Therapeutic use

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