Reason for request

Inclusion

-


Clinical Benefit

Substantial
The actual benefit of ADCETRIS is substantial in the indications of the Marketing Authorisation.

Clinical Added Value

moderate

Despite very limited data, but given the high response rate and the absence of a validated therapeutic alternative, the Transparency Committee is of the opinion that ADCETRIS offers a moderate improvement in actual benefit (IAB III) in terms of efficacy in the treatment of adults

- with relapsed or refractory CD30+ Hodgkin lymphoma following autologous stem cell transplant (ASCT) or following at least two prior therapies when ASCT or multi-agent chemotherapy is not a treatment option.

- with relapsed or refractory systemic anaplastic large cell lymphoma.


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