Reason for request
Inclusion
-
Clinical Benefit
Substantial |
The actual benefit of JAKAVI is substantial in the Marketing Authorisation indication. |
Clinical Added Value
moderate |
In view of the established efficacy on reducing splenic volume and the symptoms resulting from this, the Committee considers that JAKAVI provides a moderate improvement in actual benefit (level III) in the management of patients suffering from primary myelofibrosis or myelofibrosis secondary to polycythaemia vera or essential thrombocythaemia. |
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Évaluation des médicaments