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Opinions on drugs - Posted on Dec 16 2014

Reason for request

Extension of indication


Actual benefit


The  actual  benefit  of ABRAXANE in combination with gemcitabine is substantial in the extension of indication “first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas”

Improvement in actual benefit

IV (mineur)

ABRAXANE in combination with gemcitabine provides  a  minor  improvement  in  actual  benefit  (level  IV)  compared  with gemcitabine monotherapy in the treatment of metastatic adenocarcinoma of the pancreas, in adult patients, as first-line treatment.