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JAKAVI (ruxolitinib), protein kinase inhibitor

ONCOLOGY - New indication
Opinions on drugs - Posted on Feb 29 2016

Reason for request

Extension of inclusion

Minor improvement in second-line treatment of polycythemia vera.


  • JAKAVI now has Marketing Authorisation in the treatment of adults with polycythemia vera who are resistant or intolerant to hydroxyurea.

  • It provides a minor improvement in the short term, due to better safety and an improvement of symptoms. There are no long-term safety data.



Clinical Benefit



Clinical Added Value



Therapeutic use


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