Reason for request

Inclusion on the list of medicines approved for hospital in the new indication: “topotecan in combination with cisplatin is indicated for patients with carcinoma of the cervix recurrent after radiotherapy and for patients with Stage IV-B disease”.

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Clinical Benefit

Substantial

The actual benefit of HYCAMTIN is substantial.


Clinical Added Value

minor

HYCAMTIN combined with cisplatin only provides a minor improvement in actual benefit (IAB IV) in terms of efficacy compared to cisplatin in treatment of carcinoma of the cervix recurrent after radiotherapy and for patients with Stage IV-B disease.


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