RYBREVANT (amivantamab) - Non-small cell lung cancer (NSCLC)
Opinions on drugs -
Posted on
Aug 07 2025
Reason for request
First listing
Summary of opinion
Favourable opinion for reimbursement in combination with lazertinib for the first-line treatment of adult patients with advanced non-small cell lung cancer (NSCLC) with EGFR Exon 19 deletions or Exon 21 L858R substitution mutations.
Clinical Benefit
| Moderate |
The clinical benefit of RYBREVANT (amivantamab) 1,600 mg and 2,240 mg solution for injection is moderate in the MA indication: “in combination with lazertinib for the first-line treatment of adult patients with advanced non-small cell lung cancer (NSCLC) with EGFR Exon 19 deletions or Exon 21 L858R substitution mutations”. |
Clinical Added Value
| no clinical added value |
These medicinal products are range supplements that provide no clinical added value (CAV V) compared to the form already listed. |
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